Pletal helps blood flow more smoothly through the blood vessels; this action improves oxygen flow to the tissues of the body.
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The following adverse reactions are discussed in greater detail inother sections of the labeling:
Figure 2 depicts the percent mean improvement in maximal walking distanceat study end for each of the eight studies.
Due to cilostazol’s platelet aggregation inhibitory effect it is possible that an increased bleeding risk occurs in combination with surgeryincluding minor invasive measurements like tooth extractionIf a patient is to undergo elective surgery and antiplatelet effect is not necessarycilostazol should be stopped 5 days prior to surgery.
There are no adequate data in the use of cilostazol in pregnant womenStudies in animals have shown reproductive toxicitysee Section 5.3The potential risk for humans is unknownPletal must not be used during pregnancysee section 4.3
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