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Causal Relationship UnknownOther reactions have been reported but occurred under circumstances where a causal relationship could not be establishedHoweverin these rarely reported eventsthat possibility cannot be excludedThereforethese observations are listed to serve as alerting information to physicians.

Angiotensin-converting enzymeACEinhibitorsegenalaprilangiotensin II receptor antagonistsegvalsartancyclosporineother potassium-sparing diureticsegaldosteronetriamtereneor potassium supplements because high blood potassium levels may occur and cause listlessnessconfusionabnormal skin sensations of the arms and legsheaviness of the limbsslow or irregular heartbeator stopping of the heart Nonsteroidal anti-inflammatory drugsNSAIDsegindomethacinbecause they may decrease Midamor’s effectiveness and increase the risk of kidney problems and high blood potassium levels Lithium or quinidine because the risk of their side effects and toxicity may be increased by Midamor.

CyclosporineNeoralSandimmuneGengraftacrolimusPrograflithiuman ACE inhibitor such as benazeprilLotensincaptoprilCapotenenalaprilVasoteclisinoprilPrinivilZestrilramiprilAltaceand othersor indomethacin or other NSAIDsnon-steroidal anti-inflammatory drugssuch as aspirinibuprofenMotrinAdvildiclofenacVoltarennaproxenAleveNaprosynpiroxicamFeldenenabumetoneRelafenetodolacLodineand others.

Contact your doctor or health care provider right away if any of these apply to you.

MIDAMORamilorideis a potassium-conservingantikaliureticdrug that possesses weakcompared with thiazide diureticsnatriureticdiureticand antihypertensive activityThese effects have been partially additive to the effects of thiazide diuretics in some clinical studiesWhen administered with a thiazide or loop diureticMIDAMORamiloridehas been shown to decrease the enhanced urinary excretion of magnesium which occurs when a thiazide or loop diuretic is used aloneMIDAMORamiloridehas potassium-conserving activity in patients receiving kaliuretic-diuretic agents.

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